Phenotypes Associated with This Genotype

Genotype
MGI:5803966

• Allelic Composition: Nr3c1^tm2.1Ljm/Nr3c1^tm2.1Ljm; Tg(Camk2a-cre)T29-1Stl/0
• Genetic Background: involves: 129S6/SvEvTac * BALB/c * C57BL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

nervous system phenotype ( J:197150 )

N • as in wild-type mice, prior treatment with glucocorticoid stress hormone followed by middle cerebral artery occlusion sensitizes neurons to excityotoxicity

abnormal response to CNS ischemic injury ( J:197150 )

• prior treatment with glucocorticoid stress hormone fail to exhibit a reduction in numbers of infiltrating monocytes after middle cerebral artery occlusion unlike in wild-type mice

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:197150 )

N • as in wild-type mice, prior treatment with glucocorticoid stress hormone followed by middle cerebral artery occlusion sensitizes neurons to excityotoxicity

abnormal response to CNS ischemic injury ( J:197150 )

• prior treatment with glucocorticoid stress hormone fail to exhibit a reduction in numbers of infiltrating monocytes after middle cerebral artery occlusion unlike in wild-type mice