Phenotypes Associated with This Genotype

Genotype
MGI:5806300

• Allelic Composition: Mfsd2a^{tm1c(KOMP)Wtsi}/Mfsd2a^{tm1c(KOMP)Wtsi}; Tg(Tek-cre)1Ywa/0
• Genetic Background: involves: C57BL/6J * C57BL/6N
• Cell Lines: EPD0853_5_E03

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

microphthalmia ( J:234197 )

• at 4 months of age, mice exhibit slightly smaller eyeballs than control mice

• however, retina layers and photoreceptor outer segment length are normal

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:234197 )

N • at 7 weeks of age, lipidomics analysis of whole eyes revealed that total levels of docosahexaenoic acid (DHA) and arachidonic acid in eye phospholipids are comparable to those in control mice