Phenotypes Associated with This Genotype

Genotype
MGI:5810135

• Allelic Composition: Bicd2^tm1Hgrd/Bicd2^tm1Hgrd; Tg(Nes-cre)1Atp/0
• Genetic Background: involves: C57BL/6 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:210236 )

• mice die by 3-4 weeks of age

nervous system

hydrocephaly ( J:210236 )

• mice develop severe progressive hydrocephalus

abnormal hippocampus layer morphology ( J:210236 )

• mice exhibit disrupted laminar organization in the hippocampus

abnormal stratification in cerebral cortex ( J:210236 )

• mice exhibit disrupted laminar organization in the cortex

abnormal cerebellar layer morphology ( J:210236 )

• mice exhibit disrupted laminar organization in the cerebellar cortex