About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:5812676
Allelic
Composition
Ptentm1Mro/Ptentm1Mro
Sdhbtm1.1Ics/Sdhb+
Tg(KLK3-cre)D4Trp/0
Genetic
Background
involves: 129S2/SvPas * FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptentm1Mro mutation (1 available); any Pten mutation (88 available)
Sdhbtm1.1Ics mutation (0 available); any Sdhb mutation (29 available)
Tg(KLK3-cre)D4Trp mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• 89% of mice show pheochromocytoma at 12.9 months of age
• tumors do not show accumulation of succinate

neoplasm
• 89% of mice show pheochromocytoma at 12.9 months of age
• tumors do not show accumulation of succinate

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
pheochromocytoma DOID:0050771 OMIM:171300
J:236514


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory