Analysis Tools
cardiovascular system
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• mice treated with tamoxifen at P1-4 show reduced vascular branching in retinal vessels at P5
• mice treated with tamoxifen at P1-4 show fewer distal sprouts with filopodia and fewer number of filopodia in the retinal vasculature
• distal sprouts have fewer side connections in the retinal vasculature of mice treated with tamoxifen at P1-4
• the radial expansion of the vascular plexus is reduced in mice treated with tamoxifen at P1-4
• vessel regression in the retina is increased in tamoxifen treated mice
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cellular
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• endothelial cell proliferation is reduced
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vision/eye
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• mice treated with tamoxifen at P1-4 show reduced vascular branching in retinal vessels at P5
• mice treated with tamoxifen at P1-4 show fewer distal sprouts with filopodia and fewer number of filopodia in the retinal vasculature
• distal sprouts have fewer side connections in the retinal vasculature of mice treated with tamoxifen at P1-4
• the radial expansion of the vascular plexus is reduced in mice treated with tamoxifen at P1-4
• vessel regression in the retina is increased in tamoxifen treated mice
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