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Phenotypes Associated with This Genotype
Genotype
MGI:5828533
Allelic
Composition		 Reg3gtm1a(KOMP)Wtsi/Reg3gtm1a(KOMP)Wtsi
Genetic
Background		 C57BL/6-Reg3gtm1a(KOMP)Wtsi
Cell Lines EPD0309_2_D08
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Reg3gtm1a(KOMP)Wtsi mutation (3 available); any Reg3g mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Orthomyxoviridae infection ( J:233979 )
• a low pathogenic A/Puerto Rico/8/1934 H1N1 (PR8M) virus-infected mice exhibit altered weight loss and recovery compared with wild-type mice
• however, mortality following infection is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory