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Phenotypes Associated with This Genotype
Genotype
MGI:6094248
Allelic
Composition		 Tap1tm1Arp/Tap1tm1Arp
X/Yaa
Genetic
Background		 BXSB.129S2(B6)-Tap1tm1Arp/Dcr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tap1tm1Arp mutation (4 available); any Tap1 mutation (51 available)
Yaa mutation (24 available); any Yaa mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to systemic lupus erythematosus ( J:179430 )
• while BXSB/MpJ males have a mean survival of 32 weeks before dying from SLE-like syndrome, the additional absence of Tap1 intensifies the severity to a mean survival of only 23 weeks of ag

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory