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Phenotypes Associated with This Genotype
Genotype
MGI:6108259
Allelic
Composition		 Hltftm1.1Hdin/Hltftm1.1Hdin
Shprhtm1Jhjh/Shprhtm1Jhjh
Genetic
Background		 involves: 129 * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hltftm1.1Hdin mutation (0 available); any Hltf mutation (47 available)
Shprhtm1Jhjh mutation (0 available); any Shprh mutation (85 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:177630 )
N
• class switch recombination in primary-activated B cells
• normal somatic hypermutation frequency and spectrum in JH4 intronic region in germinal center B cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory