Phenotypes Associated with This Genotype

Genotype
MGI:6160811

• Allelic Composition: Cpox^Rbc16/Cpox^Rbc16
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:244493 )

• embryos do not survive beyond E9.5

embryo

abnormal pharyngeal arch morphology ( J:244493 )

• underdeveloped pharyngeal arch structures

embryonic growth retardation ( J:244493 )

• E9.5 embryos exhibit severe developmental delays

• however, a vascularized yolk sac is seen indicating blood cell formation

absent forelimb buds ( J:244493 )

• embryos lack prominent forelimb bud

open neural tube ( J:244493 )

• open rostral neural tube at E9.5

growth/size/body

embryonic growth retardation ( J:244493 )

• E9.5 embryos exhibit severe developmental delays

• however, a vascularized yolk sac is seen indicating blood cell formation

limbs/digits/tail

absent forelimb buds ( J:244493 )

• embryos lack prominent forelimb bud

nervous system

open neural tube ( J:244493 )

• open rostral neural tube at E9.5

craniofacial

abnormal pharyngeal arch morphology ( J:244493 )

• underdeveloped pharyngeal arch structures