Phenotypes Associated with This Genotype

Genotype
MGI:6163484

• Allelic Composition: Greb1l^em1Cjea/Greb1l⁺
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

double ureter ( J:248902 )

• at E13.5, one of 13 male heterozygotes had a unilateral double ureter

impaired branching involved in ureteric bud morphogenesis ( J:248902 )

• at E13.5, heterozygotes show a slight decrease in ureteric bud branching relative to wild-type controls

• however, both kidneys are present and kidney volume is not significantly decreased

abnormal ureteric bud tip morphology ( J:248902 )

• at E13.5, the number of ureteric bud tips is slightly reduced