Phenotypes Associated with This Genotype

Genotype
MGI:6200278

• Allelic Composition: Elmo1^M1Btlr/Elmo1^M1Btlr
• Genetic Background: C57BL/6J-Elmo1^M1Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

increased B-1 B cell number ( J:265231 )

decreased B cell number ( J:265231 )

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:265231 )

increased CD8-positive, alpha-beta memory T cell number ( J:265231 )

decreased IgM level ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll

immune system

increased B-1 B cell number ( J:265231 )

decreased B cell number ( J:265231 )

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number ( J:265231 )

increased CD8-positive, alpha-beta memory T cell number ( J:265231 )

decreased IgM level ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll

impaired humoral immune response ( J:265231 )

• diminished T-induced B cell response to TNP-Ficoll