Analysis Tools
craniofacial
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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digestive/alimentary system
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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growth/size/body
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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• trend toward increased cellular proliferation in the tongue and esophagus in mice treated with 4NQO, a chemical carcinogen
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homeostasis/metabolism
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
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mortality/aging
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• survival of mice treated with 4NQO is less than 60% as compared to 4NQO dox-treated mice, which survive to at least 45 weeks
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neoplasm
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
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• increased incidence of gross esophageal squamous cell carcinoma with stromal invasion in mice treated with 4NQO, a chemical carcinogen, as compared to 4NQO dox-treated mice
• incidence of oral squamous cell carcinoma is not increased
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