About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6267414
Allelic
Composition
Mioxtm1Ysk/Mioxtm1Ysk
Hprt1tm1(Pck1-cre)Vhh/Hprt1+
Genetic
Background
B6.129-Mioxtm1Ysk Hprt1tm1(Pck1-cre)Vhh
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hprt1tm1(Pck1-cre)Vhh mutation (0 available); any Hprt1 mutation (1277 available)
Mioxtm1Ysk mutation (0 available); any Miox mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• mice exhibit ameliorated cisplatin-induced acute kidney injury with reduced weight loss and minimal elevation of serum creatinine or urea levels, and mild cytolysis of tubular cells and loss of brush border but no renal tubular cell apoptosis or induction of reactive oxygen species generation compared with wild-type mice

growth/size/body


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
06/12/2024
MGI 6.13
The Jackson Laboratory