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Phenotypes Associated with This Genotype
Genotype
MGI:6281137
Allelic
Composition		 Clptm1ltm1d(EUCOMM)Wtsi/Clptm1l+
Genetic
Background		 involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6N
Cell Lines EPD0460_2_E07
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Clptm1ltm1d(EUCOMM)Wtsi mutation (0 available); any Clptm1l mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal class switch recombination ( J:265892 )
• in vitro, the proportion of B cells that have undergone class-switch recombination following T cell-dependent stimulation is significantly higher than that in wild-type cells

hematopoietic system
abnormal class switch recombination ( J:265892 )
• in vitro, the proportion of B cells that have undergone class-switch recombination following T cell-dependent stimulation is significantly higher than that in wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory