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Phenotypes Associated with This Genotype
Genotype
MGI:6285509
Allelic
Composition		 Vav1M3Btlr/Vav1M3Btlr
Genetic
Background		 C57BL/6J-Vav1M3Btlr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Vav1M3Btlr mutation (0 available); any Vav1 mutation (60 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased IgG level ( J:272527 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide
impaired humoral immune response ( J:272527 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

hematopoietic system
decreased IgG level ( J:272527 )
• reduced T-dependent antibody response to ovalbumin administered with aluminum hydroxide

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory