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Phenotypes Associated with This Genotype
Genotype
MGI:6360860
Allelic
Composition
Slc2a6em1Rbr/Slc2a6em1Rbr
Genetic
Background
C57BL/6J-Slc2a6em1Rbr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc2a6em1Rbr mutation (0 available); any Slc2a6 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• females, but not males, fed a Western diet exhibit decreased adiposity
• however, food intake is not different from wild-type mice and body weight is not altered

homeostasis/metabolism
N
• whole body glucose tolerance is not affected and mice maintain normal fasting insulin levels when fed a chow or Western diet
• females fed a chow diet show lower respiratory exchange ratio during the light cycle compared to wild-type mice
• however, females fed a Western diet do not show this change in respiratory exchange ratio and females fed a Western or chow diet show similar oxygen consumption and locomotor activity to wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory