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Phenotypes Associated with This Genotype
Genotype
MGI:6360937
Allelic
Composition
St3gal5tm1Rlp/St3gal5tm1Rlp
Genetic
Background
involves: C57BL/6JJmsSlc
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
St3gal5tm1Rlp mutation (1 available); any St3gal5 mutation (25 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• juvenile males exhibit less spontaneous alternation in the Y-maze test
• juvenile males spent more time in the open arms of the elevated plus maze test, indicating reduced anxiety
• juvenile males show increased impulsive behaviors in the elevated plus maze test
• juvenile males and females exhibit hyperactivity in the motor activity test, Y-maze test, and elevated plus maze test
• treatment with methylphenidate hydrochloride does not ameliorate hyperactivity


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory