Phenotypes Associated with This Genotype

Genotype
MGI:6382542

• Allelic Composition: C5ar1^tm1Cge/C5ar1^tm1Cge
• Genetic Background: B6.129S4(Cg)-C5ar1^tm1Cge

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal c-wave shape ( J:214214 )

• the amplitude of the c-wave is reduced at 12 months of age, but not at 8 weeks of age

• however, no other component of the dc-ERG is different and mice show normal ERG a-waves and b-waves even at 12 months of age

homeostasis/metabolism

decreased circulating free fatty acids level ( J:214214 )

• plasma free polyunsaturdated fatty acid (linoleic acid and arachidonic acid) levels are decreased at 14 months of age