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Phenotypes Associated with This Genotype
Genotype
MGI:6404055
Allelic
Composition		 Tg(Hba-x-v-Ha-ras)TG.ACLed/0
Tg(KRT5-cre)1Tak/Tg(KRT5-cre)1Tak
Genetic
Background		 involves: C3H * C57BL/6 * FVB/NTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Hba-x-v-Ha-ras)TG.ACLed mutation (1 available)
Tg(KRT5-cre)1Tak mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
increased incidence of tumors by chemical induction ( J:120797 )
• quicker progression from papillomas to malignant skin tumors in TPA-treated mice
• however, the number of TPA-induced papillomas is normal

neoplasm
increased incidence of tumors by chemical induction ( J:120797 )
• quicker progression from papillomas to malignant skin tumors in TPA-treated mice
• however, the number of TPA-induced papillomas is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory