Phenotypes Associated with This Genotype

Genotype
MGI:6441546

• Allelic Composition: Gpr89^ex/Gpr89^ex
• Genetic Background: C57BL/6J-Gpr89^ex

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal T cell morphology ( J:287198 )

• increased CD44 expression in CD3+, CD4+, and CD8+ T cells

abnormal T cell number ( J:287198 )

• reduced CD3+, CD4+, and CD8+ T cell frequencies

immune system

abnormal T cell morphology ( J:287198 )

• increased CD44 expression in CD3+, CD4+, and CD8+ T cells

abnormal T cell number ( J:287198 )

• reduced CD3+, CD4+, and CD8+ T cell frequencies

growth/size/body

decreased birth body size ( J:287198 )

• 40% smaller than WT littermates