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Phenotypes Associated with This Genotype
Genotype
MGI:6505488
Allelic
Composition		 Atriptm1.1Pof/Atriptm1.1Pof
Tg(Pax6-cre,GFP)2Pgr/0
Trp53tm1Tyj/Trp53tm1Tyj
Genetic
Background		 involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atriptm1.1Pof mutation (0 available); any Atrip mutation (26 available)
Tg(Pax6-cre,GFP)2Pgr mutation (1 available)
Trp53tm1Tyj mutation (12 available); any Trp53 mutation (232 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
vision/eye
vision/eye phenotype ( J:297493 )
N
• retinas show normal morphology, lamination, and an intact outer nuclear layer, and mice exhibit a normal optomotor response
• mice show rescue of the increased apoptosis seen in the retinas of single homozygous Atrip conditional mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
06/12/2024
MGI 6.13 		The Jackson Laboratory