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Phenotypes Associated with This Genotype
Genotype
MGI:6711208
Allelic
Composition		 Podxltm1Parl/Podxltm1Parl
Podxl2tm1c(EUCOMM)Wtsi/Podxl2tm1c(EUCOMM)Wtsi
Six2tm1(tTA,tetO-EGFP/cre)Amc/Six2+
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Podxl2tm1c(EUCOMM)Wtsi mutation (0 available); any Podxl2 mutation (25 available)
Podxltm1Parl mutation (0 available); any Podxl mutation (18 available)
Six2tm1(tTA,tetO-EGFP/cre)Amc mutation (0 available); any Six2 mutation (19 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
neonatal lethality, complete penetrance ( J:240523 )
• mice die in the neonatal period

renal/urinary system
renal/urinary system phenotype ( J:240523 )
N
• mice show no obvious defects in nephron lumen formation or luminal continuity indicating normal early stages of nephrogenesis

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory