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Phenotypes Associated with This Genotype
Genotype
MGI:6712736
Allelic
Composition		 Il22tm1.1Lex/Il22tm1.1Lex
Commd10Tg(Vav1-icre)A2Kio/Commd10+
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6N * C57BL/10 * CBA/Ca
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Commd10Tg(Vav1-icre)A2Kio mutation (4 available); any Commd10 mutation (25 available)
Il22tm1.1Lex mutation (2 available); any Il22 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased erythrocyte cell number ( J:305794 )
• mice show an increase in peripheral red blood cells after treatment with phenylhydrazine to induce acute hemolytic stress

homeostasis/metabolism
decreased physiological sensitivity to xenobiotic ( J:305794 )
• mice show an increase in peripheral red blood cells after treatment with phenylhydrazine to induce acute hemolytic stress

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory