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Phenotypes Associated with This Genotype
Genotype
MGI:6715306
Allelic
Composition
Mki67em1Dfis/Mki67+
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mki67em1Dfis mutation (0 available); any Mki67 mutation (145 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
neoplasm
• 16 weeks after induction of colon tumors by azoxymethane/dextran sodium sulfate (AOM-DSS) treatment, heterozygotes show a significant increase in total lesion area (mm2) but no difference in the total number of lesions/mouse relative to similarly treated wild-type controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/17/2024
MGI 6.24
The Jackson Laboratory