Phenotypes for E2f1 Rr80 Sox9 MGI:6720292 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Sox9^tm2Crm/Sox9⁺ Rr80^em1Jwsk/Rr80⁺ E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺
Genetic Background	involves: 129S7/SvEvBrd * C3H * C57BL/6J * FVB/NJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1^{Tg(Wnt1-cre)2Sor} mutation (2 available); any E2f1 mutation (28 available)
Rr80^em1Jwsk mutation (0 available); any Rr80 mutation (0 available)
Sox9^tm2Crm mutation (1 available); any Sox9 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

craniofacial

abnormal mandible morphology ( J:306395 )

• exacerbated compared with wild-type enhancer cluster 1.45

mandibular condyloid process hypoplasia ( J:306395 )

short mandible ( J:306395 )

growth/size/body

postnatal growth retardation ( J:306395 )

skeleton

abnormal mandible morphology ( J:306395 )

• exacerbated compared with wild-type enhancer cluster 1.45

mandibular condyloid process hypoplasia ( J:306395 )

short mandible ( J:306395 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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