Analysis Tools
reproductive system
 N |
• females exhibit normal ovarian histology and follicle counts at 18 days (prepubertal), at 7 weeks, and at 7 months of age, indicating normal folliculogenesis
• when bred with wild type male mice for 6 months, adult females show normal fertility with no significant differences in average litter size or age-associated changes in fertility relative to controls
• fully grown oocytes from hyperstimulated female mice exhibit no changes in oocyte number, germinal vesicle diameter, and nuclear or nucleolar morphology
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