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Phenotypes Associated with This Genotype
Genotype
MGI:6861816
Allelic
Composition		 Thap11tm1Tpz/Thap11tm1Tpz
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
Thap11tm1Tpz mutation (0 available); any Thap11 mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal craniofacial development ( J:317822 )
• mice show almost complete agenesis of the neural crest-derived craniofacial skeleton

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory