About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:7261152
Allelic
Composition		 Samd3tm1.1(HBEGF)Wfkr/Samd3tm1.1(HBEGF)Wfkr
Genetic
Background		 C57BL/6J-Samd3tm1.1(HBEGF)Wfkr
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Samd3tm1.1(HBEGF)Wfkr mutation (0 available); any Samd3 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:322359 )
N
• mice exhibit normal response to acute Vaccinia virus or chronic Lymphocytic choriomeningitis virus infection
decreased CD8-positive, alpha-beta memory T cell number ( J:322359 )
• reduced relative and absolute numbers in mice infected with Vaccinia virus expressing ovalbumin
• however, differentiation and survival of CD8+ memory cells is normal

hematopoietic system
decreased CD8-positive, alpha-beta memory T cell number ( J:322359 )
• reduced relative and absolute numbers in mice infected with Vaccinia virus expressing ovalbumin
• however, differentiation and survival of CD8+ memory cells is normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory