Phenotypes Associated with This Genotype

Genotype
MGI:7310216

• Allelic Composition: Drc1^em1Mngx/Drc1^em1Mngx
• Genetic Background: involves: C57BL/6 * ICR

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

decreased survivor rate ( J:322334 )

• only 15.6% of mice are alive after puberty

postnatal lethality, incomplete penetrance ( J:322334 )

nervous system

hydrocephaly ( J:322334 )

• 27 of 32 prepubertal mice exhibit hydrocephaly

• however, mice that survive to adulthood show no hydrocephaly

reproductive system

absent sperm flagellum ( J:322334 )

♂ • short or absent flagella are observed in the cauda epididymis

short sperm flagellum ( J:322334 )

♂ • short or absent flagella are observed in the cauda epididymis

oligozoospermia ( J:322334 )

♂ • decreased sperm counts are observed in the cauda epididymis

cellular

absent sperm flagellum ( J:322334 )

♂ • short or absent flagella are observed in the cauda epididymis

short sperm flagellum ( J:322334 )

♂ • short or absent flagella are observed in the cauda epididymis

oligozoospermia ( J:322334 )

♂ • decreased sperm counts are observed in the cauda epididymis

growth/size/body

growth/size/body region phenotype ( J:322334 )

N • mice that survive to adulthood do not exhibit decreased body size