Phenotypes Associated with This Genotype

Genotype
MGI:7345607

• Allelic Composition: Myf5^tm3(cre)Sor/Myf5⁺; Tg(CAG-Nog)1Ych/0
• Genetic Background: involves: 129S4/SvJaeSor

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal soft palate muscle morphology ( J:310908 )

abnormal levator veli palatini muscle morphology ( J:310908 )

• myofibers in the levator veli palatini are reduced and sparser compared to controls

abnormal palatopharyngeus muscle morphology ( J:310908 )

• myofibers in the palatopharyngeus are reduced and sparser compared to controls

abnormal tensor veli palatini muscle morphology ( J:310908 )

• myofibers in the tensor veli palatini are reduced and sparser compared to controls

cleft soft palate ( J:310908 )

• at E17.5 the soft palate is still separated at the palatopharyngeus level but fused at the level of the levator veli palatini and tensor veli palatini muscles

muscle

abnormal soft palate muscle morphology ( J:310908 )

abnormal levator veli palatini muscle morphology ( J:310908 )

• myofibers in the levator veli palatini are reduced and sparser compared to controls

abnormal palatopharyngeus muscle morphology ( J:310908 )

• myofibers in the palatopharyngeus are reduced and sparser compared to controls

abnormal tensor veli palatini muscle morphology ( J:310908 )

• myofibers in the tensor veli palatini are reduced and sparser compared to controls

abnormal superior pharyngeal constrictor muscle morphology ( J:310908 )

• myofibers in the superior pharyngeal constrictor are reduced and sparser compared to controls

digestive/alimentary system

abnormal soft palate muscle morphology ( J:310908 )

abnormal levator veli palatini muscle morphology ( J:310908 )

• myofibers in the levator veli palatini are reduced and sparser compared to controls

abnormal palatopharyngeus muscle morphology ( J:310908 )

• myofibers in the palatopharyngeus are reduced and sparser compared to controls

abnormal tensor veli palatini muscle morphology ( J:310908 )

• myofibers in the tensor veli palatini are reduced and sparser compared to controls

cleft soft palate ( J:310908 )

• at E17.5 the soft palate is still separated at the palatopharyngeus level but fused at the level of the levator veli palatini and tensor veli palatini muscles

growth/size/body

abnormal soft palate muscle morphology ( J:310908 )

abnormal levator veli palatini muscle morphology ( J:310908 )

• myofibers in the levator veli palatini are reduced and sparser compared to controls

abnormal palatopharyngeus muscle morphology ( J:310908 )

• myofibers in the palatopharyngeus are reduced and sparser compared to controls

abnormal tensor veli palatini muscle morphology ( J:310908 )

• myofibers in the tensor veli palatini are reduced and sparser compared to controls

cleft soft palate ( J:310908 )

• at E17.5 the soft palate is still separated at the palatopharyngeus level but fused at the level of the levator veli palatini and tensor veli palatini muscles

respiratory system

abnormal superior pharyngeal constrictor muscle morphology ( J:310908 )

• myofibers in the superior pharyngeal constrictor are reduced and sparser compared to controls