Phenotypes Associated with This Genotype

Genotype
MGI:7414892

• Allelic Composition: Fbxl3^{em1(IMPC)Ccpcz}/Fbxl3^{em1(IMPC)Ccpcz}
• Genetic Background: C57BL/6NCrl-Fbxl3^{em1(IMPC)Ccpcz}/Ccpcz

Data Sources

IMPC Data for Fbxl3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal heart morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

digestive/alimentary system

abnormal duodenum morphology ( J:211773 )

♂

IMPC - CCP-IMG

endocrine/exocrine glands

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged testis ( J:211773 )

♂

IMPC - CCP-IMG

growth/size/body

enlarged heart ( J:211773 )

♂

IMPC - CCP-IMG

decreased lean body mass ( J:211773 )

♂

IMPC - CCP-IMG

hematopoietic system

decreased effector memory T-helper cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

homeostasis/metabolism

increased circulating alkaline phosphatase level ( J:211773 )

♂

IMPC - CCP-IMG

decreased circulating total protein level ( J:211773 )

♂

IMPC - CCP-IMG

increased circulating chloride level ( J:211773 )

♂

IMPC - CCP-IMG

immune system

decreased effector memory T-helper cell number ( J:211773 )

♂

IMPC - CCP-IMG

abnormal spleen morphology ( J:211773 )

♀

IMPC - CCP-IMG

decreased spleen weight ( J:211773 )

IMPC - CCP-IMG

integument

abnormal skin morphology ( J:211773 )

♀

IMPC - CCP-IMG

liver/biliary system

decreased liver weight ( J:211773 )

♂

IMPC - CCP-IMG

muscle

abnormal skeletal muscle morphology ( J:211773 )

♀

IMPC - CCP-IMG

nervous system

abnormal brain morphology ( J:211773 )

♂

IMPC - CCP-IMG

hydrocephaly ( J:211773 )

♂

IMPC - CCP-IMG

reproductive system

abnormal testis morphology ( J:211773 )

♂

IMPC - CCP-IMG

enlarged testis ( J:211773 )

♂

IMPC - CCP-IMG

vision/eye

abnormal retina morphology ( J:211773 )

IMPC - CCP-IMG