About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:7438238
Allelic
Composition		 E2f1Tg(Wnt1-cre)2Sor/E2f1+
Snrpbem1Lajm/Snrpb+
Trp53tm1Brn/Trp53+
Genetic
Background		 involves: 129P2/OlaHsd * C3H * C57BL/6 * CD1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
Snrpbem1Lajm mutation (0 available); any Snrpb mutation (16 available)
Trp53tm1Brn mutation (21 available); any Trp53 mutation (244 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal craniofacial morphology ( J:326544 )
• no reduction in craniofacial defects in conditional double mutant embryos at E10.5 and E17.5 compared to mutant embryos with wild-type levels of Trp53

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory