Phenotypes Associated with This Genotype

Genotype
MGI:7621295

• Allelic Composition: Cpsf6^em1Bcgen/Cpsf6⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

azoospermia ( J:346988 )

♂ • males have clear epididymides without sperm

infertility ( J:346988 )

immune system

increased interferon-beta secretion ( J:346988 )

• BMDMs infected with VSV-eGFP show greater IFN-beta production

decreased susceptibility to Riboviria infection ( J:346988 )

• bone marrow-derived macrophages (BMDMs) infected with vesicular stomatitis virus (VSV-eGFP) show lower viral load

cellular

azoospermia ( J:346988 )

♂ • males have clear epididymides without sperm