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Phenotypes Associated with This Genotype
Genotype
MGI:7657812
Allelic
Composition		 Kctd15tm1c(EUCOMM)Wtsi/Kctd15tm1c(EUCOMM)Wtsi
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * C57BL/6N
Cell Lines EPD0177_1_E09
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
Kctd15tm1c(EUCOMM)Wtsi mutation (0 available); any Kctd15 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
pigmentation
belly spot ( J:344153 )
• mice exhibit a white belly patch, a loss of pigmentation phenotype with absence of melanocytes that is pathognomonic for an NCC-derived melanoblast migration defect

integument
belly spot ( J:344153 )
• mice exhibit a white belly patch, a loss of pigmentation phenotype with absence of melanocytes that is pathognomonic for an NCC-derived melanoblast migration defect

cardiovascular system
cardiovascular system phenotype ( J:344153 )
N
• mice do not exhibit any cardiac abnormalities at PO

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory