Analysis Tools
growth/size/body
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• 26-week-old males, but not females, are resistant to age-related gain in body mass
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behavior/neurological
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• mice are impaired on a trace fear conditioning task, showing reduced freezing within the trace period after conditioning indicating reduced trace memory
• mice show reduced freezing behavior when reintroduced into context, indicating impaired contextual memory
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• mice exhibit increased anxiety-like behaviors, with mice spending less time in the open arms of the elevated plus maze and have fewer entries to these arms
• however, no difference in total exploration activity is seen
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