Phenotypes Associated with This Genotype

Genotype
MGI:7711575

• Allelic Composition: Cfdp1^tm1Dkwpd/Cfdp1^tm2.1Dkwpd; E2f1^{Tg(Wnt1-cre)2Sor}/E2f1⁺
• Genetic Background: involves: 129 * 129S2/SvPas * C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

craniofacial

abnormal craniofacial morphology ( J:349245 )

• extensive craniofacial abnormalities in the mid face region, nose, maxillary region, mandibular region, and flattened forebrain region at E16

abnormal incisor morphology ( J:349245 )

• underdeveloped with altered morphology at E16

small mandible ( J:349245 )

• small and rudimentary at E16

• consists mainly of soft tissue lacking mineralized bone at E16

short mandible ( J:349245 )

abnormal maxilla morphology ( J:349245 )

• at E16

flat head ( J:349245 )

• flattened forebrain region at E16

cellular

abnormal intracellular organelle physiology ( J:349245 )

• H2A.Z and RCC1 levels at the major satellite repeats are significantly decreased

growth/size/body

abnormal incisor morphology ( J:349245 )

• underdeveloped with altered morphology at E16

small mandible ( J:349245 )

• small and rudimentary at E16

• consists mainly of soft tissue lacking mineralized bone at E16

short mandible ( J:349245 )

abnormal maxilla morphology ( J:349245 )

• at E16

flat head ( J:349245 )

• flattened forebrain region at E16

skeleton

abnormal incisor morphology ( J:349245 )

• underdeveloped with altered morphology at E16

small mandible ( J:349245 )

• small and rudimentary at E16

• consists mainly of soft tissue lacking mineralized bone at E16

short mandible ( J:349245 )

abnormal maxilla morphology ( J:349245 )

• at E16

abnormal intramembranous bone ossification ( J:349245 )

• consists mainly of soft tissue lacking mineralized bone at E16