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Phenotypes Associated with This Genotype
Genotype
MGI:7711577
Allelic
Composition
Anp32etm1Mak/Anp32etm1Mak
Cfdp1tm1Dkwpd/Cfdp1tm2.1Dkwpd
E2f1Tg(Wnt1-cre)2Sor/E2f1+
Genetic
Background
involves: 129 * C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anp32etm1Mak mutation (1 available); any Anp32e mutation (21 available)
Cfdp1tm1Dkwpd mutation (0 available); any Cfdp1 mutation (121 available)
Cfdp1tm2.1Dkwpd mutation (0 available); any Cfdp1 mutation (121 available)
E2f1Tg(Wnt1-cre)2Sor mutation (2 available); any E2f1 mutation (28 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cellular
N
• H2A.Z and RCC1 levels at the major satellite repeats are increased in rescue mice relative to both conditional mutant mice wild-type for Anp32e and wild-type controls

craniofacial
N
• loss of Anp32e expression largely rescues the craniofacial phenotype seen in conditional mutant mice wild-type for Anp32e
• maxilla and mandible are mineralized unlike in conditional mutant mice wild-type for Anp32e


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory