Phenotypes for Rnu2-8 Snip1 MGI:7738298 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Rnu2-8^nmf291/Rnu2-8^nmf291 Snip1^em1Yiji/Snip1⁺
Genetic Background	involves: 129S4/SvJae * C57BL/6J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rnu2-8^nmf291 mutation (1 available); any Rnu2-8 mutation (1 available)
Snip1^em1Yiji mutation (0 available); any Snip1 mutation (19 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:354967 )

N	• mice exhibit rescue of the ataxia seen in Rnu2-8^{nmf291/nmf291} homozygotes

mortality/aging

extended life span ( J:354967 )

• mice exhibit extended life span compared to Rnu2-8^{nmf291/nmf291} homozygotes

nervous system

neuron degeneration ( J:354967 )

• mice exhibit partial rescue of the neuron loss seen in Rnu2-8^{nmf291/nmf291} homozygous cerebellum

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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