Nnt<C57BL/6J> Spontaneous Allele Detail MGI Mouse (MGI:3626282)

Nnt^C57BL/6J
Spontaneous Allele Detail

Summary

Symbol:	Nnt^C57BL/6J
Name:	nicotinamide nucleotide transhydrogenase; C57BL/6J
MGI ID:	MGI:3626282
Synonyms:	Ant1^-
Gene:	Nnt Location: Chr13:119472063-119545793 bp, - strand Genetic Position: Chr13, 67.21 cM, cytoband D2
Alliance:	Nnt^C57BL/6J page

Mutation
origin

Strain of Origin:

C57BL/6J

Mutation
description

Allele Type:		Spontaneous (Null/knockout)
Mutation:		Intragenic deletion
		Mutation details: This allele contains a stretch of 17,814 bp missing between exons 6 and 12. RT-PCR demonstrated cDNA corresponding to exons 7-11 was absent. Mature protein was not detected in these mutants. (J:106692, J:108213)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Nnt Mutation:	64 strains or lines available

References

Original:	J:108213 Huang TT, et al., Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum Mol Genet. 2006 Apr 1;15(7):1187-94
All:	41 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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