Sox10Dal
Chemically induced Allele Detail
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| Symbol: |
Sox10Dal |
| Name: |
SRY (sex determining region Y)-box 10; dalmatian |
| MGI ID: |
MGI:3775949 |
| Synonyms: |
Sox10M1Btlr |
| Gene: |
Sox10 Location: Chr15:79039113-79048690 bp, - strand Genetic Position: Chr15, 37.7 cM
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| Alliance: |
Sox10Dal page
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| Allele Type: |
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Chemically induced (ENU) |
| Mutation: |
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Single point mutation
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Mutation details: The mutaion is a T-to-G transversion at nucleotide position 676 of the gene (Genbank: XM_128139), in the second exon. It results in replacement of asparagine by lysine at amino acid position 131 (N131K), the terminal amino acid of the loop between the first and second alpha-helices (sometimes considered the first aa of helix II) in the DNA-binding HMG domain of the protein.
(J:132358)
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| Inheritance: |
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Dominant |
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View phenotypes and curated references for all genotypes (concatenated display).
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| Original: |
J:132358 Smart NG, et al., Dalmatian, a mouse white spotting coat color mutant allele of Sox10. MGI Direct Data Submission. 2008; |
| All: |
1 reference(s) |
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Analysis Tools
