Mrps35tm1a(EUCOMM)Wtsi
Targeted Allele Detail
|
|
| Symbol: |
Mrps35tm1a(EUCOMM)Wtsi |
| Name: |
mitochondrial ribosomal protein S35; targeted mutation 1a, Wellcome Trust Sanger Institute |
| MGI ID: |
MGI:4433487 |
| Gene: |
Mrps35 Location: Chr6:146944270-146972399 bp, + strand Genetic Position: Chr6, 77.7 cM
|
| Alliance: |
Mrps35tm1a(EUCOMM)Wtsi page
|
| IMPC: |
Mrps35 gene page |
|
| Mutant Cell Lines: |
EPD0089_3_A10, EPD0089_3_A11, EPD0089_3_B10, EPD0089_3_B12, EPD0089_3_D12, EPD0089_3_E12, EPD0089_3_G10, EPD0089_3_G11, EPD0089_3_H11, EPD0089_3_H12 |
| Germline Transmission: |
Earliest citation of germline transmission:
J:165965
|
| Parent Cell Line: |
JM8.F6 (ES Cell)
|
| Strain of Origin: |
C57BL/6N
|
| Project Collection: |
EUCOMM
|
|
| Allele Type: |
|
Targeted (Conditional ready, Null/knockout, Reporter) |
| Mutation: |
|
Insertion
Vector: L1L2_gt1
|
| |
|
Mutation details: The L1L2_gt1 cassette was inserted at position 146947144 of Chromosome 6 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 146947875. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:155845, J:173534)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
|
|
|
| Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
| All: |
4 reference(s) |
|
Analysis Tools
