Slc1a7tm1a(EUCOMM)Hmgu
Targeted Allele Detail
|
Symbol: |
Slc1a7tm1a(EUCOMM)Hmgu |
Name: |
solute carrier family 1 (glutamate transporter), member 7; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:4436714 |
Gene: |
Slc1a7 Location: Chr4:107825603-107870726 bp, + strand Genetic Position: Chr4, 50.18 cM
|
Alliance: |
Slc1a7tm1a(EUCOMM)Hmgu page
|
IMPC: |
Slc1a7 gene page |
|
Mutant Cell Line: |
HEPD0537_5_G04 |
Germline Transmission: |
Earliest citation of germline transmission:
J:165965
|
Parent Cell Line: |
JM8.N4 (ES Cell)
|
Strain of Origin: |
C57BL/6N
|
Project Collection: |
EUCOMM
|
|
Allele Type: |
|
Targeted (Conditional ready, Null/knockout, Reporter) |
Mutation: |
|
Insertion
Vector: L1L2_st0
|
|
|
Mutation details: The L1L2_st0 cassette was inserted at position 107834337 of Chromosome 4 upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 107835229. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
|
|
|
|
Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
All: |
3 reference(s) |
|