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Shc1tm1Pgp
Targeted Allele Detail
Summary
Symbol: Shc1tm1Pgp
Name: src homology 2 domain-containing transforming protein C1; targeted mutation 1, Pier G Pelicci
MGI ID: MGI:2159438
Synonyms: p66shc-, p66shc, p66Shc-
Gene: Shc1  Location: Chr3:89325858-89337336 bp, + strand  Genetic Position: Chr3, 39.11 cM
Alliance: Shc1tm1Pgp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:58535
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Not Specified
 
Mutation details: This allele is a targeted mutation of the exon that encodes the CH2 region. Further details are referenced as "in preparation". (J:58535)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shc1 Mutation:  66 strains or lines available
References
Original:  J:58535 Migliaccio E, et al., The p66shc adaptor protein controls oxidative stress response and life span in mammals [see comments]. Nature. 1999 Nov 18;402(6759):309-13
All:  57 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory