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Ackr4tm1Ccbl
Targeted Allele Detail
Summary
Symbol: Ackr4tm1Ccbl
Name: atypical chemokine receptor 4; targeted mutation 1, Conrad C Bleul
MGI ID: MGI:5316751
Synonyms: CCX-CKR1-EGFP, Ccx-ckreGFP, EGFPCCX-CKR1
Gene: Ackr4  Location: Chr9:103974881-104003842 bp, - strand  Genetic Position: Chr9, 56.47 cM
Alliance: Ackr4tm1Ccbl page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182799
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    The N-terminal half the single coding exon (exon 4) was replaced with an EGFP and neo. (J:182799)
Generation of the Ackr4tm1Ccbl allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ackr4 Mutation:  25 strains or lines available
References
Original:  J:182799 Heinzel K, et al., A silent chemokine receptor regulates steady-state leukocyte homing in vivo. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8421-6
All:  17 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory