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Tg(Acta2-cre/ERT2)1Ikal
Transgene Detail
Summary
Symbol: Tg(Acta2-cre/ERT2)1Ikal
Name: transgene insertion 1, Ivo Kalajzic
MGI ID: MGI:5461154
Synonyms: alphaSMACreERT2
Transgene: Tg(Acta2-cre/ERT2)1Ikal  Location: unknown  
Alliance: Tg(Acta2-cre/ERT2)1Ikal page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Acta2-cre/ERT2)1Ikal expression driven by 1 gene
 
Mutation details: The cre/ERT2 cDNA and BGH polyA cDNAs was inserted into a construct containing the vascular smooth muscle alpha-actin (Acta2) promoter. Functionality of the construct to modify floxed reporter constructs was tested by transient transfection of smooth muscle cell cultures. The purified vector was injected into fertilized C57BL/6 oocytes. (J:190191)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acta2 (species not specified)
Summary of all recombinase alleles driven by Acta2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:190191 Grcevic D, et al., In vivo fate mapping identifies mesenchymal progenitor cells. Stem Cells. 2012 Feb;30(2):187-96
All:  16 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory