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Tg(Calcrl,cre)4688Nkza
Transgene Detail
Summary
Symbol: Tg(Calcrl,cre)4688Nkza
Name: transgene insertion 4688, Kazu Nakazawa
MGI ID: MGI:5523525
Synonyms: mossy cell/CA3-cre
Transgene: Tg(Calcrl,cre)4688Nkza  Location: unknown  
Alliance: Tg(Calcrl,cre)4688Nkza page
Transgene
origin
Strain of Origin:  C57BL/6NTac
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Calcrl,cre)4688Nkza expression driven by 1 gene
 
Mutation detailsA 50.9 kb BAC (#RP23-202K13) containing the 5'-transcriptional regulatory region of the murine calcitonin receptor-like (Calcrl) gene was coinjected with a nuclear localization signal (nls)-cre cDNA with an HSP70 minimal promoter, into fertilized C57BL/6NTac oocytes. A line was established from mice of founder line 4688, with insertion of the transgene and cre cDNA occurring at a single locus. (J:197654)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Calcrl (mouse)
Summary of all recombinase alleles driven by Calcrl.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:197654 Jinde S, et al., Hilar mossy cell degeneration causes transient dentate granule cell hyperexcitability and impaired pattern separation. Neuron. 2012 Dec 20;76(6):1189-200
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory