Alg13tm1a(EUCOMM)Hmgu
Targeted Allele Detail
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| Symbol: |
Alg13tm1a(EUCOMM)Hmgu |
| Name: |
asparagine-linked glycosylation 13; targeted mutation 1a, Helmholtz Zentrum Muenchen GmbH |
| MGI ID: |
MGI:5578482 |
| Gene: |
Alg13 Location: ChrX:143100962-143157446 bp, + strand Genetic Position: ChrX, 65.42 cM, cytoband F2
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| IMPC: |
Alg13 gene page |
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| Mutant Cell Lines: |
HEPD0991_1_A02, HEPD0991_1_B02, HEPD0991_1_B04, HEPD0991_1_C03, HEPD0991_1_E02, HEPD0991_1_F02, HEPD0991_1_G04 |
| Germline Transmission: |
Unknown
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| Parent Cell Line: |
JM8A3.N1 (ES Cell)
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| Strain of Origin: |
C57BL/6N-Atm1Brd
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| Project Collection: |
EUCOMM
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| Allele Type: |
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Targeted (Conditional ready, Null/knockout, Reporter) |
| Mutation: |
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Insertion
Vector: L1L2_GT0_LF2A_LacZ_BetactP_neo
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Mutation details: The L1L2_GT0_LF2A_LacZ_BetactP_neo cassette was inserted at position 143101971 of Chromosome X upstream of the critical exon(s) (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of the targeted exon(s) at position 143103293. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml
(J:157065)
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| Original: |
J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015; |
| All: |
1 reference(s) |
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Analysis Tools
