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Gene Expression Data
Assay Details
Assay
Reference: J:83956 Bladt F, et al., The murine Nck SH2/SH3 adaptors are important for the development of mesoderm-derived embryonic structures and for regulating the cellular actin network. Mol Cell Biol. 2003 Jul;23(13):4586-97
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3663635
Gene symbol: Nck2
Gene name: non-catalytic region of tyrosine kinase adaptor protein 2
Reporter: lacZ
Direct Detection
Assay notes: Fixative was 1.6% formaldehyde-0.2% glutaraldehyde.
Results
Specimen 4d: embryonic day 7.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS11: embryo Weak Uniform 4d
TS11: allantois Strong 4d
TS11: extraembryonic component Strong 4d
TS11: head mesenchyme Strong 4d
Specimen 4e: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: primitive streak Present Regionally restricted 4e Expression is in the node.
TS13: future brain Present 4e
TS13: neural tube Present 4e
TS13: somite Present 4e
Specimen 4f: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: primitive streak Present Regionally restricted 4f Expression is in the node.
TS13: future brain Present 4f
TS13: neural tube Present 4f
TS13: somite Present 4f
Specimen 5a: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present Regionally restricted 5a Expression is in the caudal extremity.
Specimen 5b: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5b
TS13: foregut-midgut junction endoderm Present 5b
TS13: future spinal cord neural plate Present 5b
TS13: hindgut diverticulum endoderm Present 5b
TS13: midgut endoderm Present 5b
TS13: paraxial mesenchyme Present 5b
TS13: notochord Present Regionally restricted 5b Expression is caudal.
Specimen 5c: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5c
TS13: foregut-midgut junction endoderm Present 5c
TS13: future spinal cord neural plate Present 5c
TS13: hindgut diverticulum endoderm Present 5c
TS13: midgut endoderm Present 5c
TS13: notochordal plate Present 5c
TS13: paraxial mesenchyme Present 5c
Specimen 5d: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5d
TS13: foregut-midgut junction endoderm Present 5d
TS13: future spinal cord neural plate Present 5d
TS13: hindgut diverticulum endoderm Present 5d
TS13: midgut endoderm Present 5d
TS13: somite Present 5d
Specimen 5e: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5e
TS13: foregut-midgut junction endoderm Present 5e
TS13: future spinal cord neural plate Present 5e
TS13: hindgut diverticulum endoderm Present 5e
TS13: midgut endoderm Present 5e
TS13: somite Present 5e
Specimen 5f: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5f
TS13: foregut-midgut junction endoderm Present 5f
TS13: future spinal cord neural plate Present 5f
TS13: hindgut diverticulum endoderm Present 5f
TS13: midgut endoderm Present 5f
TS13: notochord Present 5f
Specimen 5g: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum endoderm Present 5g
TS13: foregut-midgut junction endoderm Present 5g
TS13: hindgut diverticulum endoderm Present 5g
TS13: midgut endoderm Present 5g
TS13: notochord Present 5g
Specimen 5h: embryonic day 8.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS13: future prosencephalon Present 5h
Specimen 5k: embryonic day 8.5; Nck2tm2Paw/Nck2tm2Paw (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 5k
TS13: heart Absent 5k
Specimen 6g: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Strong Regionally restricted 6g Expression is in motorneurons.
TS17: dorsal root ganglion Strong 6g
TS17: notochord Present 6g
TS17: tail somite Present 6g
TS17: trunk somite Present 6g
Specimen Not Shown: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: common atrial chamber Absent
Specimen 6j: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: brain ventricular layer Strong 6j Expression was present in the neuroepithelium of the ventricles.
Specimen 6k: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Strong Regionally restricted 6k Expression is in motorneurons.
TS17: tail sclerotome Present 6k
TS17: trunk sclerotome Present 6k
Specimen 6l: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: neural tube lateral wall Strong Regionally restricted 6l Expression is in motorneurons.
TS17: notochord Present 6l
Specimen 6m: embryonic day 10.5; Nck2tm2Paw/Nck2+ (more )
Structure Level Pattern Image Note
TS17: optic cup inner layer Strong 6m
TS17: arterial system Present 6m
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/29/2024
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