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Gene Expression Data
Assay Details
Assay
Reference: J:157819 Shimogori T, et al., A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75
Assay type: RNA in situ
MGI Accession ID: MGI:4450784
Gene symbol: Foxg1
Gene name: forkhead box G1
Probe: UI-M-BH2.3-aoj-c-09-0-UI.s1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen S6q: embryonic day 12.5 (more )
Note: Double labeled: blue - Foxg1; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS20: telencephalon Present S6_q
Specimen S6r: embryonic day 12.5; Shhtm2Amc/Shhtm2Amc, Tg(Nkx2-1-cre)2Sand/0 (more )
Note: Conditional mutant. Double labeled: blue - Foxg1; brown - Shh (assay MGI:4452154).
Structure Level Pattern Image Note
TS20: forebrain Present S6_r Expression is not expanded in the diencephalon of mutant animals.
Specimen Foxg1 - E11.5: embryonic day 11.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS19: diencephalon lateral wall mantle layer Ambiguous Foxg1-Shh E11.5-coronal , Foxg1-Shh E11.5-sagittal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
TS19: diencephalon lateral wall ventricular layer Ambiguous Foxg1-Shh E11.5-sagittal , Foxg1-Shh E11.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
TS19: telencephalon mantle layer Very strong Non-Uniform Foxg1-Shh E11.5-sagittal , Foxg1-Shh E11.5-coronal There is very strong staining in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
TS19: telencephalon ventricular layer Very strong Foxg1-Shh E11.5-coronal , Foxg1-Shh E11.5-sagittal There is very strong staining in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Foxg1 - E12.5: embryonic day 12.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS20: cerebral cortex intermediate zone Very strong Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal There is very strong staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS20: cerebral cortex ventricular layer Very strong Foxg1-Shh E12.5-coronal , Foxg1-Shh E12.5-sagittal There is very strong staining in the ventricular zone of the cerebral cortex.
TS20: cortical plate Very strong Foxg1-Shh E12.5-coronal , Foxg1-Shh E12.5-sagittal There is very strong staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS20: diencephalon mantle layer Ambiguous Foxg1-Shh E12.5-coronal , Foxg1-Shh E12.5-sagittal Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
TS20: diencephalon ventricular layer Ambiguous Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS20: ganglionic eminence Very strong Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal There is very strong staining in the ventricular and mantle zones of the ganglionic eminences.
TS20: hypothalamus mantle layer Very strong Non-Uniform Foxg1-Shh E12.5-coronal , Foxg1-Shh E12.5-sagittal There is very strong staining in the mantle zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the mantle zone of the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS20: hypothalamus ventricular layer Very strong Non-Uniform Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal There is very strong staining in the ventricular zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS20: thalamus mantle layer Ambiguous Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS20: thalamus ventricular layer Ambiguous Foxg1-Shh E12.5-sagittal , Foxg1-Shh E12.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Foxg1 - E14.5: embryonic day 14.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS22: cerebral cortex intermediate zone Very strong Foxg1-Shh E14.5-coronal , Foxg1-Shh E14.5-sagittal There is very strong staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS22: cerebral cortex ventricular layer Very strong Foxg1-Shh E14.5-sagittal , Foxg1-Shh E14.5-coronal There is very strong staining in the ventricular zone of the cerebral cortex.
TS22: cortical plate Very strong Foxg1-Shh E14.5-coronal , Foxg1-Shh E14.5-sagittal There is very strong staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS22: diencephalon mantle layer Ambiguous Foxg1-Shh E14.5-sagittal , Foxg1-Shh E14.5-coronal Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
TS22: diencephalon ventricular layer Ambiguous Foxg1-Shh E14.5-sagittal , Foxg1-Shh E14.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
TS22: ganglionic eminence Very strong Foxg1-Shh E14.5-coronal , Foxg1-Shh E14.5-sagittal There is very strong staining in the ventricular and mantle zones of the ganglionic eminences.
TS22: hypothalamus mantle layer Very strong Non-Uniform Foxg1-Shh E14.5-coronal , Foxg1-Shh E14.5-sagittal There is very strong staining in the mantle zone of the dorsal and ventral POAs and weak staining in the AVH. Staining is either absent or ubiquitous in the mantle zone of the PVH, VMH and ARH nuclei and anterior and posterior IDs.
TS22: hypothalamus ventricular layer Very strong Non-Uniform Foxg1-Shh E14.5-coronal , Foxg1-Shh E14.5-sagittal There is very strong staining in the ventricular zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the ventricular zone of the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
TS22: thalamus mantle layer Ambiguous Foxg1-Shh E14.5-sagittal , Foxg1-Shh E14.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS22: thalamus ventricular layer Ambiguous Foxg1-Shh E14.5-sagittal , Foxg1-Shh E14.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Foxg1 - E16.5: embryonic day 16.5 (more )
Note: Specimen was also hybridized with a fluorescein-labeled Shh probe (MGI:2110655; detected with TBT/BCIP). The results are reported in Supp. Table 4, whose legend includes a key to the abbreviations used and more fully details the regions examined.
Structure Level Pattern Image Note
TS24: cerebral cortex intermediate zone Very strong Foxg1-Shh E16.5-sagittal , Foxg1-Shh E16.5-coronal There is very strong staining in the postmitotic neurons in the intermediate zone of the cerebral cortex.
TS24: cerebral cortex ventricular layer Very strong Foxg1-Shh E16.5-coronal , Foxg1-Shh E16.5-sagittal There is very strong staining in the ventricular zone of the cerebral cortex.
TS24: cortical plate Very strong Foxg1-Shh E16.5-coronal , Foxg1-Shh E16.5-sagittal There is very strong staining in the postmitotic neurons in the cortical plate of the cerebral cortex.
TS24: diencephalon mantle layer Ambiguous Foxg1-Shh E16.5-sagittal , Foxg1-Shh E16.5-coronal Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones.
TS24: diencephalon ventricular layer Ambiguous Foxg1-Shh E16.5-sagittal , Foxg1-Shh E16.5-coronal Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
TS24: ganglionic eminence Very strong Foxg1-Shh E16.5-coronal , Foxg1-Shh E16.5-sagittal There is very strong staining in the ventricular and mantle zones of the ganglionic eminences.
TS24: hypothalamus mantle layer Very strong Non-Uniform Foxg1-Shh E16.5-sagittal , Foxg1-Shh E16.5-coronal There is very strong staining in the MZ of the dorsal and ventral POAs and the SCH nucleus and moderate, scattered staining in the AVH and DAH. Staining is either absent or ubiquitous in the MZ of the PVH, DMH, VMH and ARH nculei and the PH.
TS24: hypothalamus ventricular layer Very strong Non-Uniform Foxg1-Shh E16.5-coronal , Foxg1-Shh E16.5-sagittal There is very strong staining in the ventricular zone of the dorsal and ventral POAs. Staining is either absent or ubiquitous in the ventricular zone of the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
TS24: thalamus mantle layer Ambiguous Foxg1-Shh E16.5-sagittal , Foxg1-Shh E16.5-coronal Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
TS24: thalamus ventricular layer Ambiguous Foxg1-Shh E16.5-coronal , Foxg1-Shh E16.5-sagittal Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
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