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Gene Expression Data
Assay Details
Assay
Reference: J:163909 Bilguvar K, et al., Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature. 2010 Sep 9;467(7312):207-10
Assay type: RNA in situ
MGI Accession ID: MGI:4830768
Gene symbol: Wdr62
Gene name: WD repeat domain 62
Probe: WDR62 cDNA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4a E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex subventricular zone Present 4A E14.5 Expression is enriched in these zones.
TS22: cerebral cortex ventricular layer Present 4A E14.5 Expression is enriched in these zones.
Specimen 4a E15.5: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex subventricular zone Present 4A E15.5 Expression is enriched in these zones.
TS23: cerebral cortex ventricular layer Present 4A E15.5 Expression is enriched in these zones.
Specimen 4a E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex subventricular zone Present 4A E16.5 Expression is enriched in these zones.
TS24: cerebral cortex ventricular layer Present 4A E16.5 Expression is enriched in these zones.
Specimen S5a: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch Present S5_A
TS15: diencephalon Present S5_A
TS15: future midbrain Present S5_A
TS15: telencephalon Present S5_A
TS15: future hindbrain Present Regionally restricted S5_A Expression is present in the future metencephalon.
Specimen S5b: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: branchial arch Present S5_B
TS17: forelimb bud Present S5_B
TS17: nasal process Present S5_B
TS17: telencephalon Present S5_B
Specimen S5c: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: branchial arch Present S5_C
TS19: diencephalon Present S5_C
TS19: forelimb bud Present S5_C
TS19: hindlimb bud Present S5_C
TS19: metencephalon Present S5_C
TS19: midbrain Present S5_C
TS19: tail Present S5_C
TS19: telencephalon Present S5_C
TS19: trunk somite Present S5_C
Specimen S5d: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted S5_D Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: telencephalon septum Present Regionally restricted S5_D Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex subventricular zone Present S5_D Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex ventricular layer Present S5_D Expression is present in proliferating neuronal progenitors in the neuroepithelium.
Specimen S5e: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted S5_E Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: telencephalon septum Present Regionally restricted S5_E Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex subventricular zone Present S5_E Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex ventricular layer Present S5_E Expression is present in proliferating neuronal progenitors in the neuroepithelium.
Specimen S5f: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted S5_F Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: telencephalon septum Present Regionally restricted S5_F Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex subventricular zone Present S5_F Expression is present in proliferating neuronal progenitors in the neuroepithelium.
TS22: cerebral cortex ventricular layer Present S5_F Expression is present in proliferating neuronal progenitors in the neuroepithelium.
Specimen Not shown: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebral cortex subventricular zone Present Expression is present in proliferating neuronal progenitors in the neuroepithelium. Expression levels are reduced from those seen earlier.
TS25: cerebral cortex ventricular zone Present Expression is present in proliferating neuronal progenitors in the neuroepithelium. Expression levels are reduced from those seen earlier.
Specimen S5g: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: cerebellum Strong Regionally restricted S5_G Expression is present in proliferating granule neuron precursors in the external granular layer.
TS25: inferior colliculus Absent S5_G
TS25: medulla oblongata Absent S5_G
Specimen S5h: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: cerebellum external granule cell layer Strong S5_H Expression is present in proliferating granule neuron precursors.
TS28: inferior colliculus Absent S5_H
TS28: medulla oblongata Absent S5_H
Specimen Not shown: postnatal day 9 (more )
Structure Level Pattern Image Note
TS28: brain Present Expression levels are dramatically reduced compared to those seen earlier.
Specimen S5i: postnatal day 21 (more )
Structure Level Pattern Image Note
TS28: hippocampus Weak S5_I
TS28: piriform cortex Weak S5_I
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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09/17/2024
MGI 6.24 		The Jackson Laboratory